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NAITO Research Group
Laboratory for Engineered Biomaterials

News & Updates

Research Papers

【論文】Formulation-Driven Control of mRNA Polyplex Physicochemical Properties Enables Spleen-Targeted Systemic Delivery

【論文】Formulation-Driven Control of mRNA Polyplex Physicochemical Properties Enables Spleen-Targeted Systemic Delivery

【論文】Formulation-Driven Control of mRNA Polyplex Physicochemical Properties Enables Spleen-Targeted Systemic Delivery

3月30日

【論文】Delivery of Circular RNAs into Splenic Immune Cells via Intravenous Administration of Polyaspartamide Derivatives Polyplexes

【論文】Delivery of Circular RNAs into Splenic Immune Cells via Intravenous Administration of Polyaspartamide Derivatives Polyplexes

【論文】Delivery of Circular RNAs into Splenic Immune Cells via Intravenous Administration of Polyaspartamide Derivatives Polyplexes

3月27日

【論文】Effects of Amino Side Chain Chemistry on Polyaspartamide-based Polyplexes for mRNA Delivery

【論文】Effects of Amino Side Chain Chemistry on Polyaspartamide-based Polyplexes for mRNA Delivery

【論文】Effects of Amino Side Chain Chemistry on Polyaspartamide-based Polyplexes for mRNA Delivery

2月25日

【論文】Strain amplitude sweep testing of oscillatory shear of transient networks with controlled network structures

【論文】Strain amplitude sweep testing of oscillatory shear of transient networks with controlled network structures

【論文】Strain amplitude sweep testing of oscillatory shear of transient networks with controlled network structures

2月24日

【論文】Heteroduplex oligonucleotide technology boosts gene knockdown in cardiac and skeletal muscles

【論文】Heteroduplex oligonucleotide technology boosts gene knockdown in cardiac and skeletal muscles

【論文】Heteroduplex oligonucleotide technology boosts gene knockdown in cardiac and skeletal muscles

2月10日

【論文】Release mechanism of micrometer-scale particles from transient networks with well-controlled structures

【論文】Release mechanism of micrometer-scale particles from transient networks with well-controlled structures

【論文】Release mechanism of micrometer-scale particles from transient networks with well-controlled structures

2025年8月21日

【論文】Silica-coated polyion complexes for enhanced pulmonary messenger RNA delivery with optimized silica layer stability

【論文】Silica-coated polyion complexes for enhanced pulmonary messenger RNA delivery with optimized silica layer stability

【論文】Silica-coated polyion complexes for enhanced pulmonary messenger RNA delivery with optimized silica layer stability

2025年8月15日

【論文】Enhanced accumulation of heteroduplex oligonucleotides in skeletal muscles by single oligonucleotide-loaded unit polyion complexes

【論文】Enhanced accumulation of heteroduplex oligonucleotides in skeletal muscles by single oligonucleotide-loaded unit polyion complexes

【論文】Enhanced accumulation of heteroduplex oligonucleotides in skeletal muscles by single oligonucleotide-loaded unit polyion complexes

2025年8月1日

【論文】Structurally dynamic polyplexes enhance sentinel lymph node delivery of antisense oligonucleotides to inhibit breast cancer recurrence and metastasis

【論文】Structurally dynamic polyplexes enhance sentinel lymph node delivery of antisense oligonucleotides to inhibit breast cancer recurrence and metastasis

【論文】Structurally dynamic polyplexes enhance sentinel lymph node delivery of antisense oligonucleotides to inhibit breast cancer recurrence and metastasis

2025年6月20日

【論文】Investigating the impact of strand length distribution on nonlinear relaxation in transient networks

【論文】Investigating the impact of strand length distribution on nonlinear relaxation in transient networks

【論文】Investigating the impact of strand length distribution on nonlinear relaxation in transient networks

2025年6月18日

【論文】Increasing polycation hydrophobicity in mRNA polyplex vaccines enhances the efficacy of humoral and cellular immunity induction

【論文】Increasing polycation hydrophobicity in mRNA polyplex vaccines enhances the efficacy of humoral and cellular immunity induction

【論文】Increasing polycation hydrophobicity in mRNA polyplex vaccines enhances the efficacy of humoral and cellular immunity induction

2025年6月18日

【論文】Amphiphilic polyaspartamide derivatives with cholesterol introduction enhanced Ex vivo mRNA transfection effeciency to natural killer cells

【論文】Amphiphilic polyaspartamide derivatives with cholesterol introduction enhanced Ex vivo mRNA transfection effeciency to natural killer cells

【論文】Amphiphilic polyaspartamide derivatives with cholesterol introduction enhanced Ex vivo mRNA transfection effeciency to natural killer cells

2025年6月4日

【論文】Encapsulation of Small Extracellular Vesicles into Selectively Disassemblable Shells of PEGylated Metal-Phenolic Network

【論文】Encapsulation of Small Extracellular Vesicles into Selectively Disassemblable Shells of PEGylated Metal-Phenolic Network

【論文】Encapsulation of Small Extracellular Vesicles into Selectively Disassemblable Shells of PEGylated Metal-Phenolic Network

2025年6月4日

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